KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
9.09
Human Site:
S673
Identified Species:
18.18
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S673
H
K
L
K
T
S
L
S
N
Q
P
K
L
D
E
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S802
H
K
L
K
T
S
L
S
N
Q
P
K
L
D
E
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
A624
K
L
K
Y
E
E
K
A
T
K
D
L
E
R
Y
Dog
Lupus familis
XP_536002
930
105612
S673
H
K
L
K
T
S
L
S
N
Q
P
K
L
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
K648
S
Y
R
K
F
R
A
K
I
C
P
G
E
N
Q
Rat
Rattus norvegicus
NP_001009535
919
103710
L669
N
Q
P
K
L
D
E
L
F
Q
S
Q
N
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
L660
P
S
A
E
E
D
R
L
E
I
E
G
L
A
S
Chicken
Gallus gallus
NP_001006508
916
103017
A665
K
L
D
K
M
L
C
A
Q
I
D
K
K
P
K
Frog
Xenopus laevis
NP_001079545
925
103654
D669
L
S
N
Q
Q
I
L
D
K
L
F
Q
S
Q
E
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
Q661
F
T
I
A
T
L
K
Q
S
L
N
L
L
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
E527
R
K
A
T
T
S
T
E
S
S
F
Q
A
P
L
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
R684
S
Q
P
D
N
E
E
R
K
L
R
A
L
A
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
0
100
N.A.
13.3
13.3
N.A.
6.6
13.3
13.3
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
13.3
100
N.A.
26.6
46.6
N.A.
13.3
26.6
26.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
9
0
0
9
17
0
0
0
9
9
17
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
17
0
9
0
0
17
0
0
25
0
% D
% Glu:
0
0
0
9
17
17
17
9
9
0
9
0
17
9
42
% E
% Phe:
9
0
0
0
9
0
0
0
9
0
17
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% G
% His:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
9
17
0
0
0
0
0
% I
% Lys:
17
34
9
50
0
0
17
9
17
9
0
34
9
0
17
% K
% Leu:
9
17
25
0
9
17
34
17
0
25
0
17
50
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
9
0
0
0
25
0
9
0
9
9
0
% N
% Pro:
9
0
17
0
0
0
0
0
0
0
34
0
0
17
0
% P
% Gln:
0
17
0
9
9
0
0
9
9
34
0
25
0
9
9
% Q
% Arg:
9
0
9
0
0
9
9
9
0
0
9
0
0
9
0
% R
% Ser:
17
17
0
0
0
34
0
25
17
9
9
0
9
9
9
% S
% Thr:
0
9
0
9
42
0
9
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _